• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A glue needle syringe (10), comprising a syringe body, a needle guard (12), comprising a flexible tip (14), an outer sleeve (18), which is movable along an longitudinal axis (X1) between an advanced position, where it covers the needle, and a retracted position, where it does not cover the needle, and a collar (16b), which is mounted with a radial clearance (J1) around an end portion (82) of the syringe body and which has at least one pin (160) engaged in a guide opening (180) of the sleeve. A portion (143) of the flexible tip (14) fills the radial clearance (J1) between the end portion (82) of the syringe body and the collar (16b) when the tip (14) is mounted on the syringe, so that the collar is immobilized in rotation around the end portion of the syringe body as long as the tip (14) is mounted on the syringe.
    公开号:FR3037807A1
    申请号:FR1555748
    申请日:2015-06-23
    公开日:2016-12-30
    发明作者:Antoine Aneas
    申请人:Biocorp Production SA；
    IPC主号:
    专利说明:

    [0001] The present invention relates to a syringe with a glued needle, in particular a syringe of the pre-filled type.
    [0002] WO-A-2013 / 134,465 discloses a glued needle syringe equipped with a needle guard. This needle guard is a soft tip into which the needle is inserted. Its function is to keep the needle clean, that is to say to avoid contamination of an active ingredient contained in the syringe body and protect the needle against any external mechanical aggression. The syringe also includes an after-use safety system, whose function is to protect the needle at the end of the injection. This helps to avoid getting hurt with the needle when it is removed from the patient's body and to fight the transmission of diseases, such as HIV. The safety system comprises an outer sleeve which is movable along a longitudinal axis of the syringe against an elastic force generated by a spring, between an advanced position, or it covers the needle, and a retracted position, where the needle is discovered. The security system also includes a collar, which is rotatably mounted about an end portion of the syringe body. This collar comprises a pin which is engaged in a radial opening of the sleeve, which forms a guide for the pin. During an injection, the sleeve bears against the skin of the patient and can no longer rotate about its axis of revolution to guide the pin in the opening. The fact that the collar is rotatably mounted around the end portion of the syringe body therefore guides the pin in the opening of the sleeve, although the latter is immobile in rotation about its axis. With the material described in WO-A-2013 / 134,465, a misinformed user can rotate the outer sleeve about its axis, thereby causing the collar to rotate about the end portion of the syringe body. The flexible tip is attached to the collar, so that it rotates together with the collar. Material chips are therefore likely to penetrate inside the needle and contaminate the active ingredient during injection because the hollow needle has a beveled end.
    [0003] In addition, a radial clearance is defined between the collar and the end portion of the syringe body to allow rotation of the collar. There is therefore also a radial clearance between the flexible tip and the end portion of the syringe body. Bacteria can thus infiltrate through this radial clearance in the internal volume of the tip, that is to say near the needle. These bacteria can then enter the needle when the tip is removed.
    [0004] It is to these drawbacks that the invention more particularly intends to remedy by proposing a syringe with glued needle with which the risk of contamination of the active ingredient are lower. To this end, the invention relates to a glued needle syringe, comprising a syringe body, a needle guard, comprising a flexible tip, an outer sleeve, which is movable along a longitudinal axis between an advanced position, where it covers the needle, and a retracted position, where it does not cover the needle, and a collar, which is mounted with a radial clearance around an end portion of the syringe body and which comprises at least one pin engaged in a guide opening of the sleeve.
    [0005] According to the invention, a portion of the flexible tip fills the radial clearance between the end portion of the syringe barrel and the collar when the tip is mounted on the syringe, so that the collar is immobilized in rotation. around the end portion of the syringe body as the tip is mounted on the syringe. Thanks to the invention, the tip is arranged such that there is sufficient adhesion to prevent the collar from rotating around it when mounted on the needle. Thus, the outer sleeve of the security system is also locked in rotation about its axis until the flexible tip has been removed from the needle, which limits the risk of contamination. According to advantageous but not obligatory aspects of the invention, a glued needle syringe may comprise one or more of the following features, taken in any technically permissible combination: The portion of the flexible tip is compressed radially between the portion of the invention. end of the syringe body and the collar when the needle guard is mounted on the syringe; 25 - The needle guard comprises a rigid sheath surrounding the flexible tip; - The sheath is in two parts detachable from each other by a relative rotational movement between the two parts or by a relative axial movement between the two parts, while the collar forms a first portion of the sheath; - A radial clearance exists between the flexible tip and the second portion of the sheath; - The tip and the sheath are linked in translation parallel to the longitudinal axis; - The sheath comprises two opposite annular shoulders which delimit between them a receiving volume of an annular bead belonging to the flexible tip; - The collar comprises attachment tabs on the syringe body, these tabs not opposing the rotation of the collar around the end portion of the syringe body when the tip is removed from the needle; The syringe comprises locking means of the sleeve in the advanced position at the end of the injection. - The syringe is a pre-filled syringe. The invention and other advantages thereof will become more clearly apparent from the following description of an embodiment of a glued needle syringe according to its principle, made by way of example only and with reference to the accompanying drawings in which: - Figures 1, 3, 5, 7, 9, 11 and 13 each show a side view of a syringe needle sticked according to the invention, in a particular step 2, 4, 6, 8, 10, 12 and 14 each represent a longitudinal section of the syringe corresponding to the figures mentioned above, FIG. 15 is a longitudinal and larger partial section. Scale along line XV-XV in FIG. 2; FIGS. 16 to 18 are longitudinal sections showing steps of assembling the device of FIG. 15 on a glued needle syringe. Each of FIGS. 1 to 14 shows a syringe with a glued needle 1. This syringe 1 is of the pre-filled type and extends along a longitudinal axis X1. It comprises a syringe body 2 of glass, which is generally tubular and centered on the axis X1. The body 2 has a syringe nose 8 having an external recess 80. The syringe nose 8 includes a distal end portion 82 which extends from the external recess 80. A hollow needle 10 is glued into the interior of the syringe. an axial hole through the nose 8, that is opening into the internal volume of the syringe body 2, in which is stored an active ingredient P, such as a drug. The needle 10 has a distal end 102 cut into a bevel. The syringe 1 also comprises a piston rod 4 which is linked in translation with a seal 6. More precisely, the rod 4 has a threaded end which is screwed inside a thread provided in the seal 6. The seal 6 serves as a piston for ejecting the active ingredient P through the hollow needle 10, which is why the seal 6 is commonly called a "piston" or "piston seal". At the opposite axial end of the seal 6, the rod 4 comprises a pallet 42 on which the user can exert a thrust force towards the nose 8. The rod 4 is displaceable in translation relative to the body 2 along the axis X1 that is, it is slidable within the syringe body 2. In this description, the forward or distal direction means a direction parallel to the longitudinal axis X1 and facing the the epidermis of the patient under normal conditions of use of the syringe 1, while the rear or proximal direction is oriented opposite to the injection zone, the side of the pallet 42. The syringe 1 comprises , at the front, a device D for protecting the needle 10. This device D is adapted to be mounted on the nose 8 of the syringe 2. The device D 5 comprises a needle guard 12 which allows a on the other hand, to keep the needle clean prior to the use of syringe 1 and, on the other hand, to protect the needle 10 against any external mechanical action. For example, the needle guard 12 prevents the needle 10 from bending or breaking before use. The needle guard 12 is rigid and comprises a flexible tip 14 in which the needle 10 is inserted and a rigid sheath 16 which surrounds the tip 14. The tip 14 is made of elastomer, for example rubber or thermoplastic material injectable, while the rigid sheath 16 is plastic, in the example high density polyethylene (HDPE). The needle guard 12 is best seen in FIG. 15. As shown in this figure, the tip 14 has an annular bead 141 and, at the back of the bead 15, a skirt 143 surrounding the end portion 82 of the bead 14. 8. The rigid sheath 16 is in two parts 16a and 16b which are detachable from each other by a relative rotational movement between these two parts. Indeed, the two parts of the sheath 16a and 16b are interconnected by breakable bridges 162, designed to be broken when applying a moment M1 of relative rotation between the two parts of the sheath 16a and 16b . Part 16a is disposed at the front of part 16b. The parts 16a and 16b are each tubular in shape centered on the longitudinal axis X1. The tip 14 and the front portion 16a of the sheath 16 are translationally connected along the axis X1. Indeed, the bead 141 projects radially inside a peripheral housing 016a formed on the inner radial surface of the portion 16a. This peripheral housing 016a is delimited by two shoulders 168 and 169 opposite axially to one another. As shown in Figure 15, the housing 016a is opening outwardly of the sheath 16 over a portion of the circumference of this sheath. On the portion of the sheath visible in Figure 2, the housing 016a does not open outwardly of the sheath 16. The character opening the housing 016a is optional. The tip 14 can be mounted from the front inside the sheath 16 by temporarily compressing the bead 141. There is a radial clearance J2 between the outer surface of the nozzle 14 and the inner surface of the portion 16a. As the tip 14 has a decreasing diameter as it moves forward, the corresponding radial clearance J 2 decreases backward. The tip 14 is thus arranged inside the part 16a so that it is not integral in rotation with the latter. Furthermore, the front end axial surfaces S14 and S16, respectively of the endpiece 14 and the sheath 16, are flush. The rear portion 16b of the sheath 16 forms a collar which is snapped around the nose 8 of the syringe 1. The collar 16b thus comprises means for fixing around the nose 8 of the syringe 1 formed by elastic tabs 166 shaped to come These legs 166 do not oppose the rotation of the collar 16b around the end portion 82 of the syringe body 2 when the tip 14 is removed from the needle. The collar 16b also comprises two diametrically opposite pins 160, which protrude radially outwards with respect to the longitudinal axis X1. There is a radial clearance J1 between the collar 16b and the end portion 82 of the nose 8. When the tip 14 is in place on the syringe 1, the skirt 143 of the tip 14 fills the radial clearance J1 between the collar 16b and the end portion 82 of the nose 8. Specifically, the skirt 143 is compressed radially between the end portion 82 and the collar 16b. This makes it possible to ensure the seal between the internal volume of the tip 14 and the outside and thus to prevent the infiltration of bacteria in the vicinity of the needle, as could happen with the WO-A material. 465. In addition, the adhesion between the tip 14 and the collar 16b prevents it from rotating around the end portion 82 of the nose 8. On the other hand, as soon as the tip 14 is removed. of the syringe 1, the collar 16b is free to rotate around the nose 8 because of the radial clearance J2 existing between the two parts. The protection device D also includes a safety system after use, which has the function of protecting the needle at the end of injection. This safety system comprises an outer sleeve 18, which is arranged coaxially around the rigid sheath 16. The sleeve 18 is made of opaque material, to completely hide the needle 10. This sleeve 18 defines an internal radial edge 182 at the its front end and two openings 180 in which the pins 160 are respectively engaged. In the example, the pins 160 do not protrude outside the openings 160. The openings 180 serve as a guide for the pins 160. Each opening 180 is generally asymmetrical Y-shaped, with the branches of the Y which are extend backward. The branches of the Y are referenced 180a and 180c, while its central portion is referenced 180b. This central portion 180b is a straight portion, that is to say a corridor. The device D also comprises locking means of the sleeve 18 in the advanced position, which are activated at the end of the injection. In the example, these locking means are formed by a housing 180d which extends from the branch 180c forwardly. The outer sleeve 18 is axially movable, i.e. along the axis X1, between an advanced position, where it covers the needle 10 and a retracted position, where the needle 5 is uncovered. The security system comprises elastic return means of the outer sleeve 18 in the advanced position. These return means comprise a helical spring 20 which is interposed between the internal axial flange 182 of the sleeve 18 and a shoulder 165 formed on the rear portion 16b of the rigid sheath 16. The coil spring 20 has a step to the right, it is that is, the winding direction of the spring 10 is on the right. This means that the spring 20 is wound on the right, or clockwise, when looking at the spring 20 from the bottom in Figures 1 to 14, that is to say the rear side. Below are described different steps of use of the syringe 1 with reference to Figures 1 to 14.
    [0006] First, the user must remove the rigid needle guard 12 in order to perform the injection. To do this, it applies the moment M1 around the axis X1, as shown in Figure 2, to rotate the front portion 16a relative to the rear portion 16b and break the bridges 162. This is possible because the rear portion 16b of the sheath 16, that is to say the collar, is immobile in rotation around the syringe nose 8 due to the adhesion with the skirt 143 of the tip 14. Once the bridges 162 broken, the user can remove the front portion 16a of the rigid sheath 16, as represented by the arrow F1 in Figure 2. The removal of the portion 16a integrally causes the removal of the tip 14 by cooperation of the bead 141 with the shoulder back 168 of housing 016a.
    [0007] The collar 16b can then freely rotate around the nose 8 because the radial clearance J1 is no longer filled by the skirt 143 of the nozzle 14. The tip 14 and the front portion 16a of the sheath 16 are removed from the syringe 1 by a translation along the arrow F1, without rotating the tip 14 around the needle 10, so that the distal end 102 of the needle 10, bevelled, does not form chips of material likely to The withdrawal of the tip 14 and the front portion 16a of the sheath 16 brings the syringe 1 in the configuration of FIGS. 3 and 4. In this configuration, the needle 10 is completely covered by As long as the syringe 1 has not been used, the pins 160 of the rear part 16b of the sheath 16 are housed in the branch 180a of the recesses 180.
    [0008] Referring to Figures 5 and 6, when the syringe 1 is brought against the epidermis of a patient, the adhesion between the front end of the sleeve 18 and the skin prevents the sleeve 18 from rotating about its axis. The pressure exerted by the sleeve 18 on the skin causes the sleeve 18 to retract, as represented by the arrows F2 in FIG. 6. The spring 20 is then compressed, the needle 10 penetrates into the epidermis and the pins 160 become move from the branch 180a to the central portion 180b. The displacement of the pins 160 inside the openings 180 is possible because the collar 16b carrying the pins 160 is free to rotate around the nose 8. The sleeve 18 then backs around the syringe body 2 and the needle 10 is not discovered until the syringe 1 is brought against the epidermis of the patient, unlike the materials according to WO-A-2013/134465 and WO-A-2007/077463, where the needle is partly uncovered before the syringe is brought against the body of the patient. In other words, the sleeve 18 is not moved back before the injection to reveal the needle 10. Thus, there is no risk of accidental puncture before injection.
    [0009] The further movement brings the outer sleeve 18 to its retracted position, in which it no longer covers the needle 10. The continuation of the movement is carried out until the pins 160 arrive at the bottom of the corridor 180b of the recesses 180 as shown in FIGS. 7 and 8. In the configuration of FIGS. 7 and 8, the needle 10 of the syringe 1 is fully sunk into the epidermis of the patient. The user can then press the pallet 42 of the rod 4 to eject the active ingredient P contained inside the syringe 1 in the body of the patient, as represented by the arrow F4 in FIG. withdraws the syringe 1 from the patient's body, the outer sleeve 18 is resiliently returned to the advanced position by the spring 20, as represented by the arrows F3 in FIG. 10. The outer sleeve 18 then returns to overlap the needle 10 and the pins 160 slide in the corridor 180b of the recesses 180 towards the branch 180c. The syringe 1 is then in the configuration of FIGS. 11 and 12, which corresponds to an end-of-injection configuration. If, after use of the syringe 1, an awkward user presses on the sleeve 18, that is to say, tries to retract the sleeve 18, the pins 160 then move in the housing 180d of the recesses 180 and the displacement of the sleeve 18 to the rear is blocked, as shown in Figures 13 and 14. This is an additional security since the needle 10 can not be discovered at the end of injection. More specifically, the movement of the pins 160 of the branch 180c towards the housing 180d is favored because the spring 20 has a direction of winding on the right. Indeed, this spring 20 exerts, when compressed, a torque on the sleeve 18 which is directed, because of its winding direction, in the counterclockwise direction as seen from above in FIG. that is to say when looking at the syringe 1 on the side of the needle 10. This pair makes it possible to prevent the pins 160 from returning towards the corridor 160b if the user tries to retract the sleeve 18 after the 'injection. This pair also makes it possible to correctly guide the pins 160 in the corridor 180b to the branch 180c of the recesses 180 since the spring 20 exerts a torque on the collar 16b which is directed, because of its direction of winding, in the direction time in top view in Figure 9, that is to say when looking at the syringe 1 on the side of the needle 10.
    [0010] Figures 16 to 18 show the mounting steps of the protection device D on the nose 8 of the syringe body 2. A first step of mounting the protection device D is to bring the device D of the nose 8, as shown by the arrow F5 in FIG. 16. By continuing the approach movement in the direction of the arrow F5, the elastic tabs 166 are then deformed in a centrifugal radial direction F6 in contact with the nose 8, as can be seen in FIG. 17 Once the tabs 166 have passed the recess 80 of the nose 8, they snap against the latter by elastic return of the material, as represented by the arrows F7 in FIG. 18. The nose 8 of the syringe 1 is shaped to block the release of the legs 166.
    [0011] As a variant not shown, other return means that a spring can be envisaged to return the outer sleeve 18 in the advanced position at the end of injection. In a variant not shown, a single recess 180 is formed in the sleeve 18. Similarly, the sleeve may delimit a number of recesses 180 strictly greater than two, for example equal to three. In a variant that is not shown, the parts 16a and 16b of the sheath 16 can be screwed to one another or linked by another rotary locking mechanism, for example of the bayonet type. In all cases, the parts 16a and 16b are detachable from each other by a relative rotational movement between the two parts.
    [0012] Alternatively, the rod 4 and the seal 6 are dissociated, that is to say that the rod 4 is simply provided to push the seal 6. According to another variant not shown, the two parts 16a and 16b of the sheath 16 are detachable from each other by a relative axial movement between the two parts. For example, the front portion 16b can be detached from the collar 16a simply by pulling the portion 16b away from the collar 16a or by tilting the portion 16b relative to the collar 16a, that is, by off-centering the portion 16b with respect to a central axis of the collar 16a. The features of the variants and embodiments contemplated above may be combined with one another to generate new embodiments of the invention.
    权利要求:
    Claims (10)
    [0001]
    Claims 1. A syringe (1) with a stuck needle (10), comprising: a body (2) of a syringe, a needle guard (12), comprising a flexible tip (14), an outer sleeve (18), which is movable along a longitudinal axis (X1) between an advanced position, where it covers the needle, and a retracted position, where it does not cover the needle, and a collar (16b), which is mounted with a radial clearance (J1) around an end portion (82) of the syringe body (2) and which comprises at least one pin (160) engaged in a guide opening (180) of the sleeve, characterized in that a portion (143) of the flexible tip (14) fills the radial clearance (J1) between the end portion (82) of the syringe body and the collar (16b) when the tip (14) is mounted on the syringe, so that the collar is immobilized in rotation about the end portion of the syringe body as the tip (14) is mounted on the syringe.
    [0002]
    2. A syringe according to claim 1, characterized in that the portion (143) of the flexible tip (14) is compressed radially between the end portion (82) of the syringe body and the collar (16b) when the needle guard (12) is mounted on the syringe.
    [0003]
    3. A syringe according to claim 1 or 2, characterized in that the needle cover (12) comprises a rigid sheath (16) enveloping the flexible tip (14).
    [0004]
    4.- syringe according to claim 3, characterized in that the sheath is in two parts (16a, 16b) detachable from one another by a movement (M1) of relative rotation between the two parts or by axial movement relative between the two parts and in that the collar (16b) forms a first portion of the sheath.
    [0005]
    5. A syringe according to claim 4, characterized in that a radial clearance (J2) exists between the flexible tip (14) and the second portion (16a) of the sheath (16).
    [0006]
    6. The syringe according to one of claims 3 to 5, characterized in that the tip (14) and the sheath (16) are linked in translation parallel to the longitudinal axis (X1). 3037807 11
    [0007]
    7. A syringe according to claim 6, characterized in that the sheath (16) comprises two opposite annular shoulders (168, 169) which delimit between them a volume (016) for receiving an annular bead (141) belonging to the soft tip.
    [0008]
    8. A syringe according to one of the preceding claims, characterized in that the collar (16b) comprises tabs (166) for attachment to the syringe body, these tabs not opposing the rotation of the collar around the end portion (82) of the syringe body (2) when the tip is removed from the needle. 5
    [0009]
    9. A syringe according to one of the preceding claims, characterized in that it comprises means (180d) for locking the sleeve (18) in the advanced position at the end of injection. 10
    [0010]
    10. The syringe according to one of the preceding claims, characterized in that the syringe is a pre-filled syringe (1).
    类似技术:
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    同族专利:
    公开号 | 公开日
    PL3313477T3|2020-02-28|
    CN107810022A|2018-03-16|
    JP6691143B2|2020-04-28|
    BR112017027583A2|2018-08-28|
    RU2017144911A|2019-06-24|
    CN107810022B|2020-07-17|
    WO2016207196A1|2016-12-29|
    EP3313477B1|2019-07-31|
    US20180177955A1|2018-06-28|
    PT3313477T|2019-10-18|
    US10661027B2|2020-05-26|
    JP2018518317A|2018-07-12|
    ES2743957T3|2020-02-21|
    RU2698062C2|2019-08-22|
    EP3313477A1|2018-05-02|
    AU2016282807A1|2018-01-18|
    CA2989706A1|2016-12-29|
    RU2017144911A3|2019-07-24|
    AU2016282807B2|2020-11-05|
    FR3037807B1|2017-08-11|
    引用文献:
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    WO2015022787A1|2013-08-14|2015-02-19|テルモ株式会社|Syringe|WO2017089259A1|2015-11-27|2017-06-01|Sanofi-Aventis Deutschland Gmbh|An injection device|
    FR3063909A1|2017-03-17|2018-09-21|Biocorp Production|NEEDLE PROTECTION DEVICE FOR A PRE-FILLED SYRINGE NEEDLE SYRINGE AND SYRINGE COMPRISING SUCH A DEVICE|
    TWI633903B|2017-04-21|2018-09-01|戴浙|Device for preloading medicament pouch syringe|
    TWI637761B|2017-05-05|2018-10-11|薩摩亞商艾得卡醫療股份有限公司|Closed system dispensing device|
    FR3074424B1|2017-12-06|2021-11-05|Biocorp Prod|AFTER-USE SAFETY SYSTEM FOR A GLUED NEEDLE SYRINGE AND SYRINGE EQUIPPED WITH SUCH A SYSTEM|
    法律状态:
    2016-04-11| PLFP| Fee payment|Year of fee payment: 2 |
    2016-12-30| PLSC| Search report ready|Effective date: 20161230 |
    2017-04-28| PLFP| Fee payment|Year of fee payment: 3 |
    2018-04-27| PLFP| Fee payment|Year of fee payment: 4 |
    2020-05-14| PLFP| Fee payment|Year of fee payment: 6 |
    优先权:
    申请号 | 申请日 | 专利标题
    FR1555748A|FR3037807B1|2015-06-23|2015-06-23|SYRINGE NEEDLE COLLEE|FR1555748A| FR3037807B1|2015-06-23|2015-06-23|SYRINGE NEEDLE COLLEE|
    EP16731147.1A| EP3313477B1|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
    PT167311471T| PT3313477T|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
    BR112017027583-0A| BR112017027583A2|2015-06-23|2016-06-22|syringe with a needle attached.|
    RU2017144911A| RU2698062C2|2015-06-23|2016-06-22|Syringe with built-in needle|
    PCT/EP2016/064374| WO2016207196A1|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
    US15/738,667| US10661027B2|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
    ES16731147T| ES2743957T3|2015-06-23|2016-06-22|Syringe with attached needle|
    CN201680037229.XA| CN107810022B|2015-06-23|2016-06-22|Syringe including engagement needle|
    AU2016282807A| AU2016282807B2|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
    CA2989706A| CA2989706A1|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
    JP2017566792A| JP6691143B2|2015-06-23|2016-06-22|Syringe with joined needles|
    PL16731147T| PL3313477T3|2015-06-23|2016-06-22|Syringe comprising a bonded needle|
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